BDBM50260747 3-(1-(4-chlorophenyl)cyclobutyl)-5-(4-iodophenyl)-4-methyl-4H-1,2,4-triazole::CHEMBL498351

SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(I)cc1

InChI Key InChIKey=CCIVUCGOJMDSLK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260747   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260747(3-(1-(4-chlorophenyl)cyclobutyl)-5-(4-iodophenyl)-...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260747(3-(1-(4-chlorophenyl)cyclobutyl)-5-(4-iodophenyl)-...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260747(3-(1-(4-chlorophenyl)cyclobutyl)-5-(4-iodophenyl)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260747(3-(1-(4-chlorophenyl)cyclobutyl)-5-(4-iodophenyl)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed