BDBM50260879 3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,2,4-triazole::CHEMBL494637

SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=HYLCZNXUPJNYNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260879   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260879(3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chloropheny...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260879(3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chloropheny...)
Affinity DataIC50: 46nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260879(3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chloropheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260879(3-(4-(1H-imidazol-1-yl)phenyl)-5-(1-(4-chloropheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed