BDBM50271098 CHEMBL4129140

SMILES CC(=O)C1=C(O)C(=O)N(CCc2ccc(Cl)c(Cl)c2)C1c1ccc(Br)cc1

InChI Key InChIKey=WHVAGTFDMKXLRY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271098   

TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of USP5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of USP8 (unknown origin) expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of UCH-L1 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Caspase 3 (unknown origin) using Ac-DEVD-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human full-length wild-type N-terminal His-tagged USP7 expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271098(CHEMBL4129140)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of UCH-L3 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed