BDBM50279462 CHEMBL4171543

SMILES Clc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(NC(=O)C=C)nc2)c1

InChI Key InChIKey=IXIJKXSIADDKHR-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50279462   

TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of EphB4 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of TIE-2 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 32nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 40nMAssay Description:Inhibition of IGF1-R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 45nMAssay Description:Inhibition of VEGFR-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 58nMAssay Description:Inhibition of cMET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 69nMAssay Description:Inhibition of cKIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 180nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 200nMAssay Description:Inhibition of FGFR-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of FGFR-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed