BDBM50279462 CHEMBL4171543

SMILES Clc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(NC(=O)C=C)nc2)c1

InChI Key InChIKey=IXIJKXSIADDKHR-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50279462   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  40nMAssay Description:Inhibition of IGF1-R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  58nMAssay Description:Inhibition of cMET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  69nMAssay Description:Inhibition of cKIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  180nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of FGFR-4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  45nMAssay Description:Inhibition of VEGFR-3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  25nMAssay Description:Inhibition of VEGFR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of EphB4 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of TIE-2 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279462(CHEMBL4171543)
Affinity DataIC50:  200nMAssay Description:Inhibition of FGFR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed