BDBM50300029 6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine::CHEMBL578227
SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCN(C)CC1
InChI Key InChIKey=KZOJJUVZAJGNQV-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50300029
Affinity DataIC50: 230nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant G9a catalytic SET domain (913 to 1193 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair