BDBM50327847 1-(1-(Trifluoroacetyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea::CHEMBL1257517::US8501783, 1591::US9296693, 53
SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)C(F)(F)F)cc1
InChI Key InChIKey=HAMLMZMEEHRTDE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50327847
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 0.400nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center
Curated by ChEMBL
Department Of Entomology And University Of California Davis Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center
Curated by ChEMBL
Department Of Entomology And University Of California Davis Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.400nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair