BDBM50389001 CHEMBL2064016

SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(C)=O)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=LLRWJXJQZPQPFC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389001   

TargetC3a anaphylatoxin chemotactic receptor(Human)
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataIC50: 9.12nMAssay Description:Antagonist activity at human C3a receptor expressed in RBL-2H3 cells assessed as beta-hexosaminidase activity in cell supernatant compound preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetC3a anaphylatoxin chemotactic receptor(Human)
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human C3a receptor expressed in RBL-2H3 cells assessed as beta-hexosaminidase activity in cell supernatant by degranulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetC3a anaphylatoxin chemotactic receptor(Human)
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataEC50:  794nMAssay Description:Agonist activity at C3a receptor in dbcAMP differentiated human U937 cells assessed as increase in intracellular calcium using Fluo-R staining by mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed