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Found 3 Enz. Inhib. hit(s) with Target = 'C3a anaphylatoxin chemotactic receptor' and Ligand = 'BDBM50389001'
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataIC50:  9.12nMAssay Description:Antagonist activity at human C3a receptor expressed in RBL-2H3 cells assessed as beta-hexosaminidase activity in cell supernatant compound preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human C3a receptor expressed in RBL-2H3 cells assessed as beta-hexosaminidase activity in cell supernatant by degranulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
Princeton University

Curated by ChEMBL
LigandPNGBDBM50389001(CHEMBL2064016)
Affinity DataEC50:  794nMAssay Description:Agonist activity at C3a receptor in dbcAMP differentiated human U937 cells assessed as increase in intracellular calcium using Fluo-R staining by mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed