BDBM50420471 CHEMBL2086530

SMILES Cc1cccnc1N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)C=C)cc1

InChI Key InChIKey=LXGRQANYXIETIX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420471   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420471(CHEMBL2086530)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420471(CHEMBL2086530)
Affinity DataIC50: 340nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420471(CHEMBL2086530)
Affinity DataIC50: 990nMAssay Description:Inhibition of human TG2 in HEK cells by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420471(CHEMBL2086530)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant TG1 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase E(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420471(CHEMBL2086530)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of thrombin activated human TG3 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed