BDBM50428594 CHEMBL2337981

SMILES CC(C)(C)NC(=O)NCCN1CCC(CO)(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1

InChI Key InChIKey=RAZOFRCGTLUGNK-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50428594   

LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 600nMAssay Description:Inhibition of human T-type calcium channel Cav3.2 expressed in T-Rex293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of T-type calcium channel Cav3.2 (unknown origin) by IONWORKS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant CYP2D6-mediated 7-methoxy-4(aminomethyl)-coumarine degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of calcium channel Cav1.2 (unknown origin) expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human HCN4 channel expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Nav1.5 channel expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IONWORKS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 channel expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed