BDBM50432774 CHEMBL2348627
SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2nc(oc2c1)-c1ccncc1
InChI Key InChIKey=YUFRXADFMZVJFT-LBPRGKRZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50432774
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair