BDBM50445209 CHEMBL3103625::US9540323, Comparator 2::US9540323, example comparator 2
SMILES CC1(C)CN(c2ccccc12)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=GYKCLACFAZJLOM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50445209
Affinity DataKi: 8.70nMAssay Description:Displacement of [33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nM ΔG°: -11.0kcal/molepH: 7.4 T: 25°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 2.5 uM ADP-induced platelet aggregation preincubated for 1 min fol...More data for this Ligand-Target Pair