BDBM50446401 CHEMBL3109656

SMILES Oc1cc(cc2cc(NC(=O)Nc3ccc4c(O)cc(cc4c3)S([O-])(=O)=O)ccc12)S([O-])(=O)=O

InChI Key InChIKey=PCGISRHGYLRXSR-UHFFFAOYSA-L

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50446401   

TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of GST-tagged PRMT1 (unknown origin) incubated for 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 expressed in Escherichia coli using histone H4 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 using GST-Npl3 as substrate incubated for 15 mins prior to protein addition measured after 1 hr by colorimetric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PRMT1 (2 to end residues) expressed in baculovirus infected Sf9 insect cells using biotinylated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed