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Found 3 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 1 [11-371]' and Ligand = 'BDBM50446401'
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 using GST-Npl3 as substrate incubated for 15 mins prior to protein addition measured after 1 hr by colorimetric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 expressed in Escherichia coli using histone H4 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446401(CHEMBL3109656)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed