BDBM50449676 CHEMBL4162159

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N2)[C@@H](C)O

InChI Key InChIKey=LIKDFTWWPULYOJ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50449676   

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataKi:  49nMAssay Description:Inhibition of human cationic trypsin using Boc-VPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataKi:  81nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTrypsin-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataKi:  134nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of bovine alpha-chymotrypsin using Suc-AAPF-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human alpha thrombin using Boc-VPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human matriptase using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed