BDBM50452782 CHEMBL4210791

SMILES OC(c1ccc2N(CCSc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=NMKUHNALTSCROZ-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50452782   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50:  20nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50:  165nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50:  185nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50:  190nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50: >2.00E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORbeta ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50: >2.00E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORalpha ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at Gal4-tagged human RORbeta ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at Gal4-tagged human RORalpha ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed