BDBM50468181 CHEMBL4289841

SMILES CC(=O)Nc1cc(-c2[nH]c3cccnc3c2-c2ccc(F)nc2)ccn1

InChI Key InChIKey=MTOKESMTTXYGSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468181   

TargetTGF-beta receptor type-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50468181BDBM50468181(CHEMBL4289841)
Affinity DataIC50: 7nMAssay Description:Inhibition of wild type TGFbetaR2 (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50468181BDBM50468181(CHEMBL4289841)
Affinity DataIC50: 22nMAssay Description:Inhibition of TGFbetaR1 T204D mutant (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed