BDBM50468181 CHEMBL4289841
SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2cccnc2c1-c1ccc(F)nc1
InChI Key InChIKey=MTOKESMTTXYGSQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50468181
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of wild type TGFbetaR2 (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of TGFbetaR1 T204D mutant (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair