BDBM50500401 CHEMBL3746593

SMILES COc1ccc(NC(=O)C(=O)c2cn(CC3CCCO3)c3ccccc23)cn1

InChI Key InChIKey=LVQWUIBSUCHLDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500401   

TargetTubulin beta chain(Pig)
University of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500401(CHEMBL3746593)
Affinity DataIC50: 420nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
University of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500401(CHEMBL3746593)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed