BDBM50500403 CHEMBL3746996

SMILES COCCn1cc(C(=O)C(=O)Nc2ccc(OC)nc2)c2cccnc12

InChI Key InChIKey=DKFYLLCZNHNOHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500403   

TargetTubulin beta chain(Pig)
University of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500403(CHEMBL3746996)
Affinity DataIC50: 940nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
University of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500403(CHEMBL3746996)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed