BDBM50514964 CHEMBL4561563

SMILES COc1ccc(cc1O)-c1cc2n(-c3cc(OC)c(OC)c(OC)c3)c(=O)[nH]c2c(n1)C(N)=O

InChI Key InChIKey=WUZIEGHVPAZRFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514964   

TargetTubulin beta chain(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514964(CHEMBL4561563)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization measured every 1 min for 25 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetKatanin p60 ATPase-containing subunit A1(Homo sapiens)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514964(CHEMBL4561563)
Affinity DataKd:  9.16E+3nMAssay Description:Binding affinity to N-terminal human Katanin p60 (8 to 229 residues) expressed in Escherichia coli Rosetta (DE3) assessed as dissociation constant by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKatanin p60 ATPase-containing subunit A1(Homo sapiens)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50514964(CHEMBL4561563)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to C-terminal human Katanin p60 (111 to 491 residues) expressed in Escherichia coli Rosetta (DE3) assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed