BDBM50540804 CHEMBL4639495

SMILES Cc1c(cnn1-c1cccc(NC(=O)CCCCCCC(=O)NO)c1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=ONNBAIYKHCDJOC-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50540804   

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 830nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed