BDBM50540804 CHEMBL4639495

SMILES Cc1c(cnn1-c1cccc(NC(=O)CCCCCCC(=O)NO)c1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=ONNBAIYKHCDJOC-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50540804   

TargetHistone deacetylase 8(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  830nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed