BDBM50580203 CHEMBL5089366

SMILES CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4ccc(-c5ccoc5)c(OC)c43)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC

InChI Key InChIKey=AAWUTGDJUMVVMF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580203   

TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580203BDBM50580203(CHEMBL5089366)
Affinity DataEC50:  535nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580203BDBM50580203(CHEMBL5089366)
Affinity DataEC50:  537nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580203BDBM50580203(CHEMBL5089366)
Affinity DataEC50:  8.04E+3nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580203BDBM50580203(CHEMBL5089366)
Affinity DataEC50:  8.13E+3nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed