BDBM50581227 CHEMBL5083242

SMILES COc1nc(C)nc2[nH]cc(-c3ccncc3)c12

InChI Key InChIKey=MSJVVYBVCYREFU-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50581227   

LigandChemical structure of BindingDB Monomer ID 50581227BDBM50581227(CHEMBL5083242)
Affinity DataKi:  20nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50581227BDBM50581227(CHEMBL5083242)
Affinity DataIC50: 50nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581227BDBM50581227(CHEMBL5083242)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PAK4 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581227BDBM50581227(CHEMBL5083242)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581227BDBM50581227(CHEMBL5083242)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed