BDBM50581227 CHEMBL5083242

SMILES COc1nc(C)nc2[nH]cc(-c3ccncc3)c12

InChI Key InChIKey=MSJVVYBVCYREFU-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50581227   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581227(CHEMBL5083242)
Affinity DataKi:  20nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581227(CHEMBL5083242)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581227(CHEMBL5083242)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581227(CHEMBL5083242)
Affinity DataIC50:  50nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581227(CHEMBL5083242)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PAK4 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed