BDBM50582161 CHEMBL5076889

SMILES CC(=O)Nc1ccc(-n2nc3c(=O)[nH]nc(N)c3c2-c2oc3cc(C(=O)Nc4cccc(C(F)(F)F)c4)ccc3c2C)cc1

InChI Key InChIKey=GMVAILVBISMMBH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582161   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Bytedance Ai Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582161BDBM50582161(CHEMBL5076889)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human DDR1 (492 to end residues) using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma33P]ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Bytedance Ai Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582161BDBM50582161(CHEMBL5076889)
Affinity DataEC50:  34nMAssay Description:Inhibition of DDR1 in human THP-1 cells assessed as reduction in collagen induced DDR1 autophosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed