BDBM50666969 CHEMBL6176593

SMILES O=C(CCc1cnc(C(=O)NCc2cccnc2)cn1)c1ccc(F)c(F)c1

InChI Key InChIKey=JNMIINAGHIZOCQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50666969   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666969BDBM50666969(CHEMBL6176593)
Affinity DataIC50: 3.60E+4nMAssay Description:Negative allosteric modulation of human GluN1/GluN2A expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666969BDBM50666969(CHEMBL6176593)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of human GluN1/GluN2B expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2C(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666969BDBM50666969(CHEMBL6176593)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of human GluN1/GluN2C expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666969BDBM50666969(CHEMBL6176593)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of human GluN1/GluN2D expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed