BDBM515018 US11098044, Example 60::US11098044, Example 61
SMILES F[C@H]1C[C@H]1C(=O)Nc1cn2cc(ccc2n1)-c1cccc(F)c1C#N
InChI Key InChIKey=NLXGPUYLEYEZDV-DOMZBBRYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 515018
Affinity DataIC50: 55nMAssay Description:c-abl: ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(p-aminoethyl ether)-...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The LRRK2 and LRRK2 G2019S kinase assays were performed using the Adapta™ technology in ThermoFisher Scientific. This experiment was carried out acco...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 55nMAssay Description:The LRRK2 and LRRK2 G2019S kinase assays were performed using the Adapta™ technology in ThermoFisher Scientific. This experiment was carried out acco...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:c-abl: ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(p-aminoethyl ether)-...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The LRRK2 and LRRK2 G2019S kinase assays were performed using the Adapta™ technology in ThermoFisher Scientific. This experiment was carried out acco...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 55nMAssay Description:The LRRK2 and LRRK2 G2019S kinase assays were performed using the Adapta™ technology in ThermoFisher Scientific. This experiment was carried out acco...More data for this Ligand-Target Pair