BDBM55745 MLS000715219::N-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)-(3,4-dimethoxyphenyl)methyl]propanamide::N-[(5-chloro-8-hydroxy-7-quinolinyl)-(3,4-dimethoxyphenyl)methyl]propanamide::N-[(5-chloro-8-hydroxy-7-quinolyl)-(3,4-dimethoxyphenyl)methyl]propionamide::N-[(5-chloro-8-hydroxyquinolin-7-yl)-(3,4-dimethoxyphenyl)methyl]propanamide::SMR000275198::cid_2921752

SMILES CCC(=O)NC(c1ccc(OC)c(OC)c1)c1cc(Cl)c2cccnc2c1O

InChI Key InChIKey=ZMWXCFUGRBATKA-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55745   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM55745(N-[(5-chloro-8-hydroxyquinolin-7-yl)-(3,4-dimethox...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM55745(N-[(5-chloro-8-hydroxyquinolin-7-yl)-(3,4-dimethox...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 integrase 3'-processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM55745(N-[(5-chloro-8-hydroxyquinolin-7-yl)-(3,4-dimethox...)
Affinity DataIC50: 5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM55745(N-[(5-chloro-8-hydroxyquinolin-7-yl)-(3,4-dimethox...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay