BDBM5730 4-((1,6-dimethyl-2-oxo-1,2,3,4- tetrahydroquinolin-7-yl)amino)-2-(2,6- dioxopiperidin-3-yl)isoindoline-1,3-dione::US20240208937, Compound 33

SMILES Cc1cc2c(cc1Nc1cccc3c1C(=O)N(C1CCC(=O)NC1=O)C3=O)N(C)C(=O)CC2

InChI Key InChIKey=PVXUYPLWMVPQAL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5730   

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5730BDBM5730(4-((1,6-dimethyl-2-oxo-1,2,3,4- tetrahydroquinolin...)
Affinity DataEC50:  55nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5730BDBM5730(4-((1,6-dimethyl-2-oxo-1,2,3,4- tetrahydroquinolin...)
Affinity DataEC50:  55nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent