BDBM609383 (R)N-(1-(5-(2-((dimethylamino)methyl)phenyl)thiophen-2-yl)ethyl)-4-isopropyl-6,7-dimethoxyphthalazin-1-amine::US11702418, Example 5-1
SMILES COc1cc2c(N[C@H](C)c3ccc(s3)-c3ccccc3CN(C)C)nnc(C(C)C)c2cc1OC
InChI Key InChIKey=NREDMVQBYOREBV-GOSISDBHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 609383
Affinity DataIC50: 669nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Table 21: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair