Found 2 Enz. Inhib. hit(s) with Target = 'Son of sevenless homolog 1 [564-1049]' and Ligand = 'BDBM609383'
Affinity DataIC50: 7.20nMAssay Description:Table 21: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Affinity DataIC50: 669nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair