BDBM65506 CHEBI:80062::Chivosazole F::SCHEMBL1889389

SMILES COC1CC(O)/C=C/C=C/C=C\C(C)C(C(C)C(O)CC(C)O)OC(=O)/C=C\C=C\C=C/C(C)=C/C(C)C(O)/C=C\C=C\c2coc(n2)C1C

InChI Key InChIKey=ATQKOUYCGKRYRF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65506   

TargetActin(Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65506BDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 140nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65506BDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 270nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65506BDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 380nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed