BDBM65516 CHEBI:84382::CHEMBL2426321::Chondramide C

SMILES C/C1=C\[C@@H](C)[C@@H](C)OC(=O)C[C@H](c2ccc(O)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](C)NC(=O)[C@@H](C)C1

InChI Key InChIKey=NCRSWJPOFRASIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65516   

TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65516BDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65516BDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.51E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin(Baker's yeast)
Novartis Pharma

LigandChemical structure of BindingDB Monomer ID 65516BDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed