BDBM707645 US12168007, Example 3::US20250049786, Example 3
SMILES CCCOCN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1
InChI Key InChIKey=HLLRGSYTXGJJHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 707645
Affinity DataKi: 0.182nMAssay Description:Aliquoted membrane preparations were incubated with 0.7 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates ...More data for this Ligand-Target Pair
Affinity DataKi: 0.182nMAssay Description:Table 8: CHO-K1 cells expressing human recombinant D3 receptors were washed with PBS. Cells were scraped from the plates and centrifuged at 1000×g. C...More data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Table 3: Cultured CHO-K1 cells expressing recombinant human D2L receptors (DRD2L cAMP Hunter™, Gi cell line, Eurofins DiscoverX, Fremont, CA, USA) we...More data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Test compounds were diluted serially in DMSO and subsequently diluted to 5% DMSO (v/w) in binding buffer (50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl...More data for this Ligand-Target Pair
Affinity DataKi: 1.17nMAssay Description:Table 4: CHO-K1 cells expressing human recombinant D2L receptors were washed with phosphate-buffered saline (PBS). Cells were scraped from the plates...More data for this Ligand-Target Pair
Affinity DataKi: 1.17nMAssay Description:Aliquoted membrane preparations were incubated with 0.16 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates...More data for this Ligand-Target Pair