BDBM745339 1,3-Difluoro-8-nitroindolo[2,1-b]quinazoline-6,12-dione ::US20250171452, Compound 11

SMILES O=C1c2cc([N+](=O)[O-])ccc2-n2c1nc1cc(F)cc(F)c1c2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745339   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745339(1,3-Difluoro-8-nitroindolo[2,1-b]quinazoline-6,12-...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Viscient Bio

US Patent
LigandPNGBDBM745339(1,3-Difluoro-8-nitroindolo[2,1-b]quinazoline-6,12-...)
Affinity DataIC50: 20nMAssay Description:After equilibrating the plates and reagents, 140 μl of the supernatant was transferred to a new plate using multichannel pipette. 10 μl of 6.1N trich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent