BDBM745377 2-Fluoro-4-methyl-8-nitroindolo[2,1-b]quinazoline-6,12-dione ::US20250171452, Compound 49

SMILES Cc1cc(F)cc2c(=O)n3c(nc12)C(=O)c1cc([N+](=O)[O-])ccc1-3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745377   

LigandPNGBDBM745377(2-Fluoro-4-methyl-8-nitroindolo[2,1-b]quinazoline-...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM745377(2-Fluoro-4-methyl-8-nitroindolo[2,1-b]quinazoline-...)
Affinity DataIC50: 20nMAssay Description:After equilibrating the plates and reagents, 140 μl of the supernatant was transferred to a new plate using multichannel pipette. 10 μl of 6.1N trich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent