BDBM753987 4-(8-Fluoro-4-(3-(hydroxymethyl)piperazin-1-yl)-2-((tetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol::US20250206759, Example 20

SMILES OCC1CCCN(c2nc(OCC34CCCN3CCC4)nc3c(F)c(-c4cc(O)cc5ccccc45)ncc23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753987   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753987(4-(8-Fluoro-4-(3-(hydroxymethyl)piperazin-1-yl)-2-...)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent