BDBM753989 4-(4-(3-Amino-i-oxa-8-azaspiro[4.5]deca-8-yl)-8-fluoro-2-((tetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol::US20250206759, Example 22

SMILES NC1COC2(CCN(c3nc(OCC45CCCN4CCC5)nc4c(F)c(-c5cc(O)cc6ccccc56)ncc34)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753989   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753989(4-(4-(3-Amino-i-oxa-8-azaspiro[4.5]deca-8-yl)-8-fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent