BDBM766754 N-[3-chloro-4-(1,4,5,7-tetrahydropyrazolo[3,4-c]pyridin-6-ylmethyl)phenyl]-3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-benzamide::US12398142, Compound CD-1-051

SMILES Cc1ccc(C(=O)NC2=CC(Cl)C(CN3CCc4cn[nH]c4C3)C=C2)cc1C#Cc1cnc2cccnn12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766754   

LigandPNGBDBM766754(N-[3-chloro-4-(1,4,5,7-tetrahydropyrazolo[3,4-c]py...)
Affinity DataIC50: 9.93nMAssay Description:Compounds were tested against the Abl1 target kinase and showed potencies between 0.30 and 0.64 nanomolar, compared to nilotinib which showed a poten...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766754(N-[3-chloro-4-(1,4,5,7-tetrahydropyrazolo[3,4-c]py...)
Affinity DataIC50: 5.02E+3nMAssay Description:Compounds were tested against the Abl1 target kinase and showed potencies between 0.30 and 0.64 nanomolar, compared to nilotinib which showed a poten...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent