BDBM783167 US20250326769, Example 19

SMILES Cc1cc2n(n1)-c1ccc(F)cc1[C@@H](C)Oc1cc(cnc1N)-c1c(nn(C)c1C#N)C2=O

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783167   

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandPNGBDBM783167(US20250326769, Example 19)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandPNGBDBM783167(US20250326769, Example 19)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent