BDBM791820 US12545652, Comparative Compound A

SMILES NC(=O)c2nc(c1c(F)cccc1Cl)oc2Nc4ccc(C(=O)N3CCOCC3)cc4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 791820   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791820BDBM791820(US12545652, Comparative Compound A)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791820BDBM791820(US12545652, Comparative Compound A)
Affinity DataIC50: 49nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791820BDBM791820(US12545652, Comparative Compound A)
Affinity DataIC50: 87nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791820BDBM791820(US12545652, Comparative Compound A)
Affinity DataIC50: 290nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent