BDBM791821 US12545652, Comparative Compound B

SMILES NC(=O)c2nc(c1c(Cl)cccc1Cl)oc2Nc4ccc(C(=O)N3CCOCC3)cc4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 791821   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 5.10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 26nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 77nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 271nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 2C9(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 4.40E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 2C8(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 8.20E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 2C19(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 3.00E+4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 2D6(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 3.00E+4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 3A4(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 3.00E+4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 1A2(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 3.00E+4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent

TargetCytochrome P450 2B6(Human)
Sareum

US Patent
LigandChemical structure of BindingDB Monomer ID 791821BDBM791821(US12545652, Comparative Compound B)
Affinity DataIC50: 3.00E+4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details ArticleUS Patent