BDBM791896 (E)-3-(3-hydroxy-4 -oxo-1 ,2 ,4 ,5 -tetrahydrospiro[cyclobutane-1,3 -pyrido[2,3-b][1,4]diazepin]-8 -yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide ::US12545672, Compound 115

SMILES Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)NCC2(CC(O)C2)C(=O)N3)oc2ccccc12

InChI Key InChIKey=WGUPHAIEDZMTLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 791896   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
Debiopharm International

US Patent
LigandChemical structure of BindingDB Monomer ID 791896BDBM791896((E)-3-(3-hydroxy-4 -oxo-1 ,2 ,4 ,5 -tetrahydrospir...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent