BDBM791955 US12545673, Example 23

SMILES CCS(=O)(=O)N1CC[C@H](Nc2c(Br)cnc3nc(-c4cc(C)n(-c5cccc(S(N)(=O)=O)c5)c4C)[nH]c23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 791955   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791955BDBM791955(US12545673, Example 23)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 9(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791955BDBM791955(US12545673, Example 23)
Affinity DataIC50: 25nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 10(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791955BDBM791955(US12545673, Example 23)
Affinity DataIC50: 56nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent