BDBM792842 (2-(benzyloxy)- 4,6-dihydroxy-3- methylphenyl)(6- ((dimethylamino) methyl)-3,4- dihydroisoquinolin- 2(1H)- yl)methanone::US12552758, Example 61

SMILES Cc1c(O)cc(O)c(C(=O)N2CCc3cc(CN(C)C)ccc3C2)c1OCc1ccccc1

InChI Key InChIKey=BLSCXXJVYHZKLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 792842   

TargetMismatch repair endonuclease PMS2(Human)
Neophore

US Patent
LigandChemical structure of BindingDB Monomer ID 792842BDBM792842((2-(benzyloxy)- 4,6-dihydroxy-3- methylphenyl)(6- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details
US Patent

TargetDNA mismatch repair protein Mlh1(Human)
Neophore

US Patent
LigandChemical structure of BindingDB Monomer ID 792842BDBM792842((2-(benzyloxy)- 4,6-dihydroxy-3- methylphenyl)(6- ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details
US Patent