BDBM808355 N,N-dimethyl- 4-(2-{[(3S)- piperidin-3- yl]amino}-5- (trifluoromethyl) pyrimidin-4- yl)-1H- pyrrole-2- carboxamide::US20260137698, Compound CDK7-536

SMILES CN(C)C(=O)c1cc(-c2nc(N[C@H]3CCCNC3)ncc2C(F)(F)F)c[nH]1

InChI Key InChIKey=WYFJJHQYRACKFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 808355   

Targetcdk7/cyclinh/mnat(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808355BDBM808355(N,N-dimethyl- 4-(2-{[(3S)- piperidin-3- yl]amino}-...)
Affinity DataIC50: 10nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk9/cyclin k(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808355BDBM808355(N,N-dimethyl- 4-(2-{[(3S)- piperidin-3- yl]amino}-...)
Affinity DataIC50: 27.5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk2/cyclin a(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808355BDBM808355(N,N-dimethyl- 4-(2-{[(3S)- piperidin-3- yl]amino}-...)
Affinity DataIC50: 200nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent