BDBM808362 N4-[2- (dimethylphos- phoryl)phenyl]- N2-[(3S)- piperidin-3- yl]-5- (trifluoromethyl) pyrimidine- 2,4-diamine::US20260137698, Compound CDK7-735

SMILES CP(C)(=O)c1ccccc1Nc1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F

InChI Key InChIKey=BTRXSAGBAUFUBR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 808362   

Targetcdk7/cyclinh/mnat(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808362BDBM808362(N4-[2- (dimethylphos- phoryl)phenyl]- N2-[(3S)- pi...)
Affinity DataIC50: 10nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk9/cyclin k(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808362BDBM808362(N4-[2- (dimethylphos- phoryl)phenyl]- N2-[(3S)- pi...)
Affinity DataIC50: 27.5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk2/cyclin a(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808362BDBM808362(N4-[2- (dimethylphos- phoryl)phenyl]- N2-[(3S)- pi...)
Affinity DataIC50: 200nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent